Les patients atteints de diabète de type 2 ont un risque élevé de développer une maladie cardiovasculaire1

Une glycémie élevée est toxique pour l’organisme et entraîne inflammation et stress oxydatif.2,3,4

Cela endommage la paroi artérielle et provoque le dépôt d’une plaque, aboutissant à une athérosclérose et des complications cardiovasculaires.2,3

 

 

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.cls-1 { fill: none; stroke: #001956; stroke-linecap: round; stroke-miterlimit: 10; stroke-width: 2px; }
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Apprendre comment le GLP-1 agit dans le corps, et ce que cela signifie pour les patients atteints de diabète de type 2.
pancreas

1.

Low Wang CC, Hess CN, Hiat WR, et al. Clinical update: Cardiovascular disease in diabetes mellitus: Atherosclerosis cardiovascular disease and heart failure in type 2 diabetes mellitus – mechanisms, management, and clinical considerations. Circulation. 2016;133:2459-2502.

2.

International Diabetes Federation. Taking Diabetes to Heart Survey – Global survey on CVD awareness and knowledge among people with type 2 diabetes. Brussels, Belgium: International Diabetes Federation, 2018. www.idf.org/takingdiabetes2heart

3.

Beckman JA, Creager MA, Libby P. Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA. 2002;287:2570-2581.

4.

Bucala R, Makita Z, Koschinsky T, et al. Lipid advanced glycosylation: pathway for lipid oxidation in vivo. Proc Natl Acad Sci U S A. 1993;90:6434-6438.

5.

Einarson TR. Acs A, Ludwig C, et al. Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007-2017. Cardiovasc Diabetol. 2018;17:83.

6.

Barquera S, Pedroza-Tobias A, Medina C, et al. Global overview of the epidemiology of atherosclerotic cardiovascular disease. Arch Med Res. 2015;46:328-338.

7.

Newman JD, Schwartzbard AZ, Weintraub HS et al. Primary prevention of cardiovascular disease in diabetes mellitus. J Am Coll Cardiol. 2017;70:883-893

8.

Almdal T, Scharlinq H. Jensen JS, et al. The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death:a population-based study of 13,000 men and women with 20 years of follow-up. Arch Intem Med. 2004;164:1422-1426.

9.

Fox C, Coady S, Sorlie P, et al. Trends in cardiovascular complications of diabetes. JAMA. 2004;292:2495-2499.

10.

Robinson RG, Jorge RE. Post-stroke depression: a review. Am J Psychiatry. 2016;173:221-231.

11.

Feng HP, Chien WC, Cheng WT, et al. Risk of anxiety and depressive disorders in patients with myocardial infarction: A nationwide population-based cohort study. Medicine (Baltimore). 2016;95:e4464.

12.

Emerging Risk Factors Collaboration, Di Angelantonio E. Kaptoge S, et al. Association Of cardiometabdic multimorbidity with mortality. JAMA. 2015;314:52-60.